ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Rectal cancer history taking

Faptul c neoplasmul de colon reprezint una din principalele cauze de deces prin neoplazie justific importana acordat studiului interconexiunilor realizate ntre aciunea factorilor de mediu i modificrile genetice ce conduc la apariia acestei afeciuni. Etiopatogenia cancerului de colon I. Contact information of Romanian Statistical Review Substratul genetic al neoplaziilor Cancerul ca boal genetic Cancerul este definit ca expansiunea clonal necontrolat a celulelor ce va conduce n stadiile avansate la invadarea esuturilor adiacente i a metastazelor la distan. Evenimentele genetice iniiale ce declaneaz aceast proliferare aberant sunt urmate de acumularea de modifcri genetice suplimentare la nivelul celulelor progenitoare i n final de selectarea dintre acestea a unor subclone cu proprieti de cretere rectal cancer history taking performante ce devin dominante n cadrul tumorii.

Bogdan - Corresponding author: - 2. Pathology on the edge of interdisciplinarity.

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A historical epitome E. Vollmer, T.

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Goldmann Pathology is a bridging discipline that involves both basic and clinical biomedical sciences. In this context, it includes both descriptive and mechanistic approaches, with the final goals of further understanding the anatomic and functional changes and underlying molecular rectal cancer history taking involved in disease-related processes. Pathology studies mainly comprise macroscopic and microscopic examinations, and involve the visual rectal cancer history taking of different patterns rectal cancer history taking cells and tissues.

In time elapsed to this end, it has adopted a dazzling array of methods and techniques from the most varied fields of natural and human papilloma virus hpv) sciences in order to optimize tissue analysis, which will be summarized in this article. Corresponding author: Ekkehard Vollmer, Professor, e-mail: evollmer fz-borstel. Genetic patterns of metalloproteinases and their tissular inhibitors - clinicopathologic and prognostic significance in colorectal cancer V.

Surlin, M. Ioana, I.

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Plesea Colorectal cancer CRC is the third most common cancer in men and second in women. Progression and invasion of colorectal cancer is a multistep process involving multiple interactions between the tumor and the surrounding stroma mediated by many proteins, among them metalloproteinases MMPs and tissular inhibitors of metalloproteinases TIMPs.

Levels of MMPs genes expression in colorectal cancer correlate with the depth of invasion, hematogenous and lymphatic metastasis, poor differentiation, Duke's stage and prognosis. Levels of TIMP's genes expression correlate with better prognosis and longer survival. The methods to assess the variance in gene expression were not always the same.

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The promoter regions of metalloproteinases present many polymorphisms and all have allele-specific effects on regulation of MMP gene transcription. Numerous studies on the association of these polymorphisms with cancer susceptibility have been carried out. Most of the studies addressed one or two polymorphisms and their implications.

A meta-analysis is necessary to confirm significant correlations. The heterogenicity of the MMPs and TIMPs genetic patterns generated by different studies on colorectal cancer does not allow us to have an overall correlation with clinicopathologic variables and the prognosis of the disease. Studies that involve many MMPs, TIMPs polymorphisms rectal cancer history taking their tissular expression would be more valuable to better assess the role of those enzymes in the progression of the disease and may serve as a starting point for selective therapeutic approaches.

Rectal cancer history taking.

Extra-genitally located endometriosis I. The significance of its finding is also outlined by its less frequent localizations intestine, gall bladder, lungs and by its differentiated symptoms complicating the differential diagnosis. The definitive diagnosis can only be reached through a histopathological examination as the detection of this affliction may lead to severe therapeutic errors radical resection.

The importance rectal cancer history taking an early diagnosis may help in preventing and delaying the effects of this affliction. Histological and ultrastructural analysis of the seminiferous tubule wall in ageing testis O. Pop, Corina Gabriela Cotoi, I.

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Plesea, Mihaela Gherghiceanu, S. Enache, E. Mandache, Gratiela Hortopan, R. Plesea The authors evaluated possible morphological changes of basement membrane BM and rectal cancer history rectal cancer history taking propria LP of seminferous tubule wall ST related to ageing. Surgical samples of testicular tissue from 28 cases with orchiectomy for prostate adenocarcinoma were processed for light microscopy and transmission electron microscopy TEM examination. Seven age groups AgGr between 50 and 80 years were designed.

Tissue samples were immunomarked for collagen IV and smooth muscle actin. Images were acquired and measured with a specialized software.

rectal cancer history taking

Thirty ST were randomly selected, with xobjective, for each case. Five random determinations for each ST and each parameter were performed. Regression line RLslope and significance test for slope were determined for each parameter correlation with ageing.

BM mean value rectal cancer history taking around 0. RL showed discrete decreasing trend with ageing but without an obvious statistical correlation.

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LP mean value was around 6 micro-m, also with narrow limits of ranging in AgGr and more extended individual limits. RL decreased discretely with ageing but without an obvious statistical correlation. Our results showed that BM thickness is apparently decreasing with ageing whereas LP presents extremely variable degenerative changes, with a "mosaic", focal distribution and no tendency to advance with ageing.

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The role of endoscopic examination accompanied by histological examination on biopsy samples in the diagnosis of gastric carcinoma D.

Ghita, Aurelia Glavici, A. Saftoiu, I.

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Plesea, S. Cazacu, Claudia Georgescu, T.

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Ciurea Introduction. Endoscopic evaluation is one of the most important explorations in the diagnosis of gastric cancer, increasing its value by adding biopsy sampling and histopathologic examination, especially in early forms of gastric malignant rectal cancer history taking. The aim of this study was to evaluate some descriptive parameters of macroscopic and microscopic aspects of gastric carcinomas defined with the help of endoscopic investigation and gastric biopsies sampled during endoscopic examination, and their correlation with patient survival.

Colorectal cancer family history

Materials and Methods. The study was performed on a group of patients diagnosed with gastric carcinoma. The study material was represented by: tissue fragments obtained by endoscopic biopsy, clinical observation charts, histopathologic diagnosis records, ledgers for records of endoscopic investigation, and endoscopic images recorded for each patient.

Biopsies were taken preferentially from areas with the highest risk of malignancy. Tumor fragments were subjected to conventional histological processing techniques rectal cancer history taking and inclusion in paraffin and then were stained with HIM. The paraziți hermafroditi included two chapters: the imagistic study and the pathologic study.

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The parameters assessed were: the site of the lesion within the stomach, the endoscope macroscopic appearance, the microscopic appearance of the endoscope biopsy sample, and the survival, followed up until 48 months. Most of the tumors were restricted to a single segment of the stomach. The combined histologic and endoscopic morphologic investigation allowed the shaping of an accurate morphologic and prognostic preoperative profile in gastric carcinomas.

Morphoclinical study of intracerebral hemorrhage with subarachnoid effusion Carmen Corina Stancu, I. Enache, R.

Diaconescu, A. Camenita, Mihaela Tenovici Aim.

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The study is an integrated assessment of clinical, imagistic and morphological parameters in severe intracerebral hemorrhages ICH complicated with subarachnoid effusion SAE. The parameters evaluated were clinical relation with the seasons, age, sex, arterial blood pressure, the motor deficit, degree of coma and Glasgow score at admission and morphological the sites of the intraparenchymal hematoma and SAE, the size of the intraparenchymal hematoma, the presence of the mass effect, and the association of intraventricular effusion.

The latter were assessed on CT films and during autopsy.

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From the 37 studied cases, 18 were men and 19 women. The hematomas had huge dimensions as compared to hosting encephalic structures, in lobar sites involving more than one lobe. Other risk factors as mass effect, perilesional edema and intraventricular extension IVE were constantly present.

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The association of SAE with other independent risk factors such as hypertension, low Glasgow scores, dimensions of hemorrhagic foci, presence of mass effect, perilesional edema and intraventricular extension IVE results in the death of patient despite any sustained therapeutical intervention. Preliminary study of bipolar hip prosthesis - influence of acetabular bone interactions on bone morphology I.

Plesea, D. Anusca, Simona Bondari, O. Pop, Treatment for basal cell papilloma. Poenaru, V. Dascalu, Mirela Ghilusi Periprosthetic bone changes following hip arthroplasty are yet to be completely described.